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Cluster headache (CH)

CH is one of a group of primary headache disorders (trigeminal autonomic cephalalgias) of uncertain mechanism that are characterized by frequently recurring, short-lasting but extremely severe headache. CH also has episodic and chronic forms.

Episodic CH occurs in bouts (clusters), typically of 6-12 weeks’ duration once a year or two years and at the same time of year. Strictly one-sided intense pain develops around the eye once or more daily, mostly at night, until the pain diminishes after 30-60 minutes. The eye is red and waters, the nose runs or is blocked on the affected side and the eyelid may droop. In the less common chronic CH there are no remissions between clusters. The episodic form can become chronic, and vice versa, but once CH has struck it may recur over 30 years or more.

Though relatively uncommon (affecting fewer than 1 in 1000 adults), CH is clearly highly recognizable. It is unusual among primary headache disorders in affecting six men to each woman. Most people developing CH are in their 20s or older.

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